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2008 Iowa State Schedule
| Date | Time (ET) | Opponent | Result | Record |
| 11/14/2008 | 08:00 PM | UC Davis | W, 61-58 | 1-0 |
| 11/15/2008 | 01:30 PM | Loyola Marymount | W, 67-55 | 2-0 |
| 11/16/2008 | 08:00 PM | Milwaukee | W, 79-61 | 3-0 |
| 11/24/2008 | 11:59 PM | at Hawaii | L, 60-59 | 3-1 |
| 11/29/2008 | 01:30 PM | Miss Valley St | W, 77-59 | 4-1 |
| 12/03/2008 | 09:00 PM | at Northern Iowa | ||
| 12/06/2008 | 02:00 PM | Oregon State | ||
| 12/09/2008 | 09:00 PM | Drake | ||
| 12/12/2008 | 08:05 PM | at Iowa | ||
| 12/20/2008 | 09:00 PM | Jacksonville St | ||
| 12/23/2008 | 08:00 PM | South Dakota St | ||
| 12/28/2008 | 06:00 PM | at Houston | ||
| 12/31/2008 | 05:00 PM | Mercer | ||
| 01/03/2009 | 08:00 PM | SIU-Edwardsville | ||
| 01/06/2009 | 08:00 PM | Houston Baptist | ||
| 01/10/2009 | 04:00 PM | at Texas | ||
| 01/14/2009 | 08:00 PM | Nebraska | ||
| 01/17/2009 | 01:45 PM | at Missouri | ||
| 01/24/2009 | 02:00 PM | Kansas | ||
| 01/27/2009 | 10:30 PM | at Colorado | ||
| 01/31/2009 | 01:45 PM | Oklahoma | ||
| 02/03/2009 | 08:00 PM | at Kansas State | ||
| 02/07/2009 | 06:00 PM | Missouri | ||
| 02/11/2009 | 07:30 PM | Colorado | ||
| 02/14/2009 | 04:00 PM | at Oklahoma State | ||
| 02/18/2009 | 08:00 PM | at Kansas | ||
| 02/21/2009 | 06:00 PM | Kansas State | ||
| 02/24/2009 | 09:00 PM | Baylor | ||
| 02/28/2009 | 01:45 PM | at Texas A&M | ||
| 03/04/2009 | 07:30 PM | at Nebraska | ||
| 03/07/2009 | 01:45 PM | Texas Tech |
