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2008 Illinois Fighting Illini Schedule
| Date | Time (ET) | Opponent | Result | Record |
| 08/30/2008 | 08:30 PM | at Missouri | L, 52-42 | 0-1-0 |
| 09/06/2008 | 12:00 PM | Eastern Ill | W, 47-21 | 1-1-0 |
| 09/13/2008 | 12:00 PM | UL Lafayette | W, 20-17 | 2-1-0 |
| 09/27/2008 | 08:00 PM | at Penn State | L, 38-24 | 2-2-0 |
| 10/04/2008 | 03:30 PM | at Michigan | W, 45-20 | 3-2-0 |
| 10/11/2008 | 12:00 PM | Minnesota | L, 27-20 | 3-3-0 |
| 10/18/2008 | 08:00 PM | Indiana | W, 55-13 | 4-3-0 |
| 10/25/2008 | 12:00 PM | at Wisconsin | L, 27-17 | 4-4-0 |
| 11/01/2008 | 03:30 PM | Iowa | W, 27-24 | 5-4-0 |
| 11/08/2008 | 12:00 PM | at Western Mich | L, 23-17 | 5-5-0 |
| 11/15/2008 | 12:00 PM | Ohio State | L, 30-20 | 5-6-0 |
| 11/22/2008 | 03:30 PM | at Northwestern | L, 27-10 | 5-7-0 |
