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2008 Iowa Hawkeyes Schedule
| Date | Time (ET) | Opponent | Result | Record |
| 08/30/2008 | 12:05 PM | Maine | W, 46-3 | 1-0-0 |
| 09/06/2008 | 12:05 PM | Florida Intl | W, 42-0 | 2-0-0 |
| 09/13/2008 | 12:05 PM | Iowa State | W, 17-5 | 3-0-0 |
| 09/20/2008 | 12:00 PM | at Pittsburgh | L, 21-20 | 3-1-0 |
| 09/27/2008 | 12:05 PM | Northwestern | L, 22-17 | 3-2-0 |
| 10/04/2008 | 12:05 PM | at Michigan State | L, 16-13 | 3-3-0 |
| 10/11/2008 | 12:00 PM | at Indiana | W, 45-9 | 4-3-0 |
| 10/18/2008 | 12:00 PM | Wisconsin | W, 38-16 | 5-3-0 |
| 11/01/2008 | 03:30 PM | at Illinois | L, 27-24 | 5-4-0 |
| 11/08/2008 | 03:30 PM | Penn State | W, 24-23 | 6-4-0 |
| 11/15/2008 | 12:00 PM | Purdue | W, 22-17 | 7-4-0 |
| 11/22/2008 | 07:05 PM | at Minnesota | W, 55-0 | 8-4-0 |
